PRMT5 Data Backs Pivotal NSCLC Push: What It Means for ONC

Posted on by Eben@CANSLIM Research

In a report titled “BeOne – ADR”, the analysis argues that the updated BGB-58067 data, presented in an ESMO poster with additional follow-up, remain highly encouraging even though the headline response rate ticked lower. The report contends that the asset’s brain penetrance is a key differentiator now beginning to show through in the brain-metastasis analysis, and that the six-month duration of response and new single-arm PFS figures together support a pivotal study in second-line-plus MTAP-deficient non-small cell lung cancer in 2027.

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