Sac-TMT Lung Data Clears Bar: What It Means for Merck (MRK)

Posted on by Eben@CANSLIM Research

In a report on sac-TMT’s ESMO showing and the question of global trial translatability for Merck, the analysis argues that the China OptiTROP-Lung06 data comfortably cleared the bar and build on a growing body of evidence positioning sac-TMT as a differentiated ADC. The trial tested sac-TMT plus Keytruda against chemo plus Keytruda in first-line non-squamous non-small cell lung cancer with PD-L1 TPS below 1%, a hard-to-treat cohort where standard chemoimmunotherapy has historically been the ceiling.

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